Christian M Metallo Selected Research

Retinaldehyde (Retinal)

1/2021

Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease.

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Christian M Metallo Research Topics

Disease

36	Neoplasms (Cancer) 03/2024 - 07/2011
7	Carcinogenesis 12/2023 - 07/2011
4	Insulin Resistance 04/2024 - 04/2016
4	Obesity 12/2020 - 02/2014
3	Adenocarcinoma of Lung 01/2024 - 04/2023
3	Peripheral Nervous System Diseases (PNS Diseases) 01/2023 - 10/2019
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 04/2016
2	Lung Neoplasms (Lung Cancer) 01/2024 - 10/2023
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 01/2017
2	Disease Progression 01/2023 - 10/2020
2	Retinal Diseases 01/2023 - 01/2021
2	Liver Diseases (Liver Disease) 01/2022 - 01/2019
2	Telangiectasis (Telangiectasia) 01/2021 - 10/2019
2	Epilepsy (Aura) 01/2021 - 01/2020
2	Adenocarcinoma 01/2020 - 01/2017
2	Metabolic Diseases (Metabolic Disease) 01/2019 - 01/2018
2	Fibrosarcoma 11/2018 - 10/2018
2	Glioma (Gliomas) 01/2018 - 08/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 10/2016
1	Gestational Weight Gain 01/2024
1	Metaplasia 12/2023
1	Small Fiber Neuropathy 01/2023
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2023
1	Chronic Disease (Chronic Diseases) 01/2023
1	Sarcopenia 12/2022
1	Neoplasm Metastasis (Metastasis) 10/2022
1	Hereditary Sensory and Autonomic Neuropathies (HSAN) 10/2022
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2022
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Disease Susceptibility (Diathesis) 01/2021
1	Growth Disorders 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2021
1	Fatty Liver 12/2020
1	Inflammation (Inflammations) 10/2020
1	Alcoholic Fatty Liver 10/2020
1	Liver Neoplasms (Liver Cancer) 10/2020
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020

Drug/Important Bio-Agent (IBA)

11	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 07/2011
10	Serine (L-Serine)FDA Link 01/2023 - 07/2011
7	LipidsIBA 04/2024 - 01/2019
6	IsotopesIBA 03/2024 - 07/2011
6	Amino Acids FDA Link 01/2023 - 02/2014
5	CarbonIBA 03/2024 - 07/2011
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2024 - 11/2011
5	Glutamine (L-Glutamine)FDA Link 01/2020 - 08/2011
4	EnzymesIBA 03/2024 - 01/2018
4	CholesterolIBA 01/2024 - 04/2023
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2024 - 01/2020
4	SphingolipidsIBA 01/2023 - 10/2020
3	Surface-Active Agents (Surfactants)IBA 01/2024 - 04/2023
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2024 - 04/2023
3	Alanine (L-Alanine)FDA Link 10/2022 - 10/2020
3	Lactic Acid (Lactate)FDA LinkGeneric 10/2022 - 07/2011
3	Serine C-PalmitoyltransferaseIBA 10/2021 - 10/2019
3	Phosphotransferases (Kinase)IBA 12/2020 - 01/2017
3	alpha-hydroxyglutarateIBA 01/2018 - 12/2012
2	Biomarkers (Surrogate Marker)IBA 10/2023 - 12/2012
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2023 - 07/2011
2	Insulin (Novolin)FDA Link 01/2023 - 01/2023
2	Transcription Factors (Transcription Factor)IBA 10/2021 - 12/2017
2	Citric Acid (Citrate)FDA LinkGeneric 01/2021 - 01/2020
2	citrate-binding transport proteinIBA 01/2021 - 01/2020
2	itaconic acidIBA 01/2021 - 01/2020
2	GlutaminaseIBA 01/2020 - 01/2018
2	Mechanistic Target of Rapamycin Complex 2IBA 01/2019 - 04/2016
2	AMP-Activated Protein KinasesIBA 01/2019 - 01/2017
2	NADP (NADPH)IBA 11/2018 - 10/2018
2	isocitric acid (isocitrate)IBA 10/2018 - 11/2011
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 08/2015 - 06/2014
1	Membrane LipidsIBA 01/2023
1	Methionine (L-Methionine)FDA Link 01/2023
1	Blood Glucose (Blood Sugar)IBA 01/2023
1	thermozymocidin (myriocin)IBA 01/2023
1	Essential Amino AcidsIBA 01/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2022
1	1-deoxysphingolipidIBA 10/2022
1	NAD (NADH)IBA 10/2022
1	Matrix Metalloproteinases (MMPs)IBA 10/2022
1	Metalloproteases (Metalloproteinases)IBA 10/2022
1	Acetates (Acetic Acid Esters)FDA Link 01/2022
1	Ethanol (Ethyl Alcohol)IBA 01/2022
1	Insulin-Like PeptidesIBA 01/2021
1	CeramidesIBA 01/2021
1	SodiumIBA 01/2021
1	Carbon-13IBA 01/2021
1	Retinaldehyde (Retinal)IBA 01/2021
1	SphingosineIBA 10/2020
1	FructoseIBA 10/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2020
1	AcidsIBA 01/2020
1	Fructose-Bisphosphate Aldolase (Aldolase)IBA 01/2020
1	Mevalonic Acid (Mevalonate)IBA 01/2020
1	NVP-BKM120IBA 01/2020
1	DisulfidesIBA 01/2020
1	Cystine (L-Cystine)IBA 01/2020
1	Cysteine (L-Cysteine)FDA Link 01/2020
1	CB-839IBA 01/2020

Therapy/Procedure

8	Therapeutics 01/2024 - 02/2013
3	Immunotherapy 01/2024 - 04/2023
1	Chemoprevention 12/2023